Fontana relocated to Rome under Cardinal Girolamo Bernerio's patronage, becoming Rome's first public woman painter executing monumental altarpieces.
Between 1603 and 1604, Lavinia Fontana relocated from Bologna to Rome under the patronage of Cardinal Girolamo (Geronimo) Bernerio. In the papal capital she became, according to scholarly consensus, Rome's first public woman painter, executing large-scale public commissions including the monumental altarpiece 'Saint Hyacinth' for the basilica of Santa Sabina.
Rome at the turn of the seventeenth century was the epicenter of the art world, home to the papal court, the great Baroque building projects, and the most competitive and prestigious commissions in Christendom. For a woman to secure and execute public, monumental religious commissions in this environment — rather than working privately for individual patrons — was virtually unprecedented and marked a significant expansion of the professional space available to women artists.
Fontana's move to Rome capped decades of building reputation in Bologna and elsewhere, and it placed her at the center of Counter-Reformation artistic production during a period of intense papal investment in religious art following the Council of Trent. Her presence and success in Rome helped normalize, at least momentarily, the idea that a woman could operate at the very highest level of the era's most competitive artistic marketplace, influencing perceptions of women's capabilities among the era's most powerful religious and cultural patrons.