Gozzadini died during the Riccardina flood on 3 November 1261.
On the night of 3 November 1261, the overflow of the Idice River during the Riccardina flood led to Bettisia Gozzadini's death. This catastrophic event claimed seven lives, including Gozzadini's, who was a revered academic figure. The flood emphasizes the challenges faced by historical communities in managing natural calamities and highlights the vulnerability of even esteemed individuals in the face of nature's might. Her death was a significant loss for the academic world of Bologna and resonated widely as a moment of communal tragedy.