Mary E. Brunkow announced as a Nobel laureate in Physiology or Medicine for her work on immune tolerance.
On October 6, 2025, the Nobel Assembly at the Karolinska Institute announced that Mary E. Brunkow would share the Nobel Prize in Physiology or Medicine with colleagues Fred Ramsdell and Shimon Sakaguchi. Their award was in recognition of their pioneering discoveries in peripheral immune tolerance, specifically surrounding the role of regulatory T cells and the FOXP3 gene. This acclaim highlighted Brunkow's pivotal role in advancing immunological science and affirmed the international importance of her research into autoimmune diseases.